Mulholland Labs

Metabolic

MOTS-c

A mitochondrial-derived peptide encoded within the 12S rRNA gene. MOTS-c is studied for its role in metabolic regulation and cellular energy homeostasis.

Molecular Specifications

Molecular Weight2174.6 g/molCAS Number1627580-64-6SequenceMRWQEMGYIFYPRKLRPhysical FormLyophilized white powder

Mechanism of Action

How It Works

Research indicates MOTS-c may activate the AMPK pathway and influence folate-methionine metabolism. Studies have examined its effects on glucose regulation and fatty acid oxidation in cell and animal models.

Published Research

Research Summary

Originally characterized by Lee et al. (2015) at the USC Leonard Davis School of Gerontology. Subsequent studies have explored its metabolic effects in diet-induced obesity models and exercise physiology research, published in Cell Metabolism and related journals.

Research Use Only

The information on this page is for educational and research purposes only. It is based on published preclinical and in-vitro studies. This compound is sold for laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure, mitigate, or prevent any disease.

Available Sizes

Purchase for Research